Faculty Profile

Dr Mostafa Kamal Masud

Associate Professor

Contact Information

  • Office Address: Associate Professor Institute of Shahjalal University of Science and Technology, Sylhet-3114, Bangladesh
  • Phone: +8801819647634
  • Email: masud-bmb@sust.edu

Biography

Dr Mostafa Kamal Masud joins Shahjalal University of Science and Technology (SUST), Sylhet-3114, Bangladesh as a Lecturer at the Department of Biochemistry and Molecular Biology in April 2013 and has been promoted as an Assistant professor on April 2015. He completed his B.Sc. and M.S. from the Department of Chemistry, Shahjalal University of Science and Technology, Sylhet, Bangladesh in the year of 2009 and 2011 respectively. He obtained his PhD (major in Medical Biotechnology, Diagnosis and Nanobiotechnology) from Australian Institute for Bioengineering (AIBN), the University of Queensland (UQ) (stands 47th in the world QS World University Rankings), Brisbane, Australia in the year of 2020.

He considers himself as an emergent research leader with research capability in the field of medical technology and personalised diagnostics in Australia. His research is dedicated to the development of novel nanostructures and nano-diagnostic technologies to solve key problems in the area of medical diagnostics and treatment monitoring. As an early career researcher, he has demonstrated an exceptional track record (relative to opportunity) with 35 peer-review publications (Scopus/ Web of Science Indexed). Most of his research articles has been published in prestigious and high impact journals in the field including ACS Nano, Small, Analytical Chemistry, Biosensor and Bioelectronics, Science Advances, Nanoscale, Chemical Communication, Journal of Material Chemistry B, etc. He also contributed to two important critical perspectives on the scopes, gaps, and needs of the current medical diagnostics field which were published in Chemical Society Review and Trends in Biochemical Sciences journals. He has developed several novel readout strategies for autoantibody, miRNA and DNA methylation biomarker detection from clinical samples. These strategies are found to be simple, accurate, and portable, enabling rapid diagnosis of disease biomarkers using minimal equipment.

He has received several awards including; highly prestigious "Dean's Award for Outstanding Higher Degree by Research Theses 2020" by the University of Queensland (UQ), Australia; prestigious JSPS Postdoctoral Fellowship (2020) from Japan, Postgraduate Research Award (2018-2019) from AINSE Limited,’ Sydney; first Prize for Outstanding Poster from AINSE/ANBUG Neutron Scattering Symposium 2018, Sydney; Analytical Methods Poster Prize from 21st Australia and Newzealand Electrochemistry Symposium 2019, Brisbane, Australia. He has demonstrated the ability to work in multidisciplinary and multi-institutional teams from local and international institutes and has been affiliated as Visiting Scholar at Griffith University, Australia and Honorary Fellow at Australian Institute for Bioengineering (AIBN), the University of Queensland (UQ), Australia.

Dr Masud’s major teaching interests include Biophysical Chemistry, Enzymology, Organic Reaction Mechanism, Metabolism and Chemistry of Natural Products. His main research focuses on the design and translation of bio-favourable engineered nanostructured superparamagnetic materials towards the development of molecular diagnostics (optical and electrochemical nanobiosensors, magnetophoretic-based and paper-based microfluidic devices) for disease detection.

Education

  • PhD in Nanobiotechnology and Molecular Diagnostics (2020), Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ), Brisbane, QLD 4072, Australia.
  • M.S (Thesis) in Chemistry (2011), Department of Chemistry, Shahjalal University of Science & Technology, Sylhet-3114, Bangladesh.
  • B.Sc. (Hons.) in Chemistry (2009), Department of Chemistry, Shahjalal University of Science & Technology, Sylhet-3114, Bangladesh.

Research Interests

  • Electrochemical Biosensors
  • Molecular Diagnostics
  • Nanobiosensor
  • Nanotechnology
  • Nanozyme

Active Research Project

  • Nanostructure Integrated POC Diagnostics for Disease-Specific Biomarkers (Autoantibody, Exosomes and microRNA)
  • Nanozymes for Biosensing
  • Screening tool for Ovarian Cancer Integrating AI and ML with Nanostructured Multiplexed Platform

Previous Research Project

  • Synthesis and characterization of liquid crystalline materials for biological application.
  • Investigation of the potential of various bacteria for the aerobic degradation of engineering yarn dyes and their effluents from yarn dyeing industries.
  • Z-scan: New frontier hope at the early detection of cancer biomarker in blood plasma protein.
  • Binding Characteristics of Bovine Serum Albumin with Coomassie brilliant blue G-250.

Journal Publish

  • 1. Nguyen, N.K., Nguyen, T., Nguyen, T.K., Yadav, S., Dinh, T., Masud, M.K., Singha, P., Do, T.N., Barton, M.J., Ta, H.T. and Kashaninejad, N., Wide-Band-Gap Semiconductors for Biointegrated Electronics: Recent Advances and Future Directions. ACS Applied Electronic Materials, 2021, 3, 1959-1981.
  • 2. Zjalić, M., Mustapić, M., Glumac, Z., Prološčić, I., Blažetić, S., Vuković, N., Masud, M.K., Billah, M., Khan, A., Šegota, S., Hossain, M.S.A., Heffer, M., Construction of AC/DC magnetic syringe device for stimulated drug release, injection and ejection of nanocarriers and testing cytotoxicity in vitro, MethodsX, 2021, 8, 101312.
  • 3. Mustapić, M., Glumac, Z., Heffer, M., Zjalić, M., Prološčić, I., Masud, M.K, Blažetić, S., Vuković, A., Billah, M., Khan, A. and Šegota, S., AC/DC magnetic device for safe medical use of potentially harmful magnetic nanocarriers. Journal of Hazardous Materials, 2021, 409, 124918.
  • 4. Wahab, M.A., Na, J., Masud, M.K., Hossain, M.S.A., Alothman, A.A. and Abdala, A., Nanoporous carbon nitride with a high content of inbuilt N site for the CO2 capture. Journal of Hazardous Materials, 2021, 408, 124843
  • 5. Wahab, M. A., Li, H., Zhang, H., Deng, J., Zhai, X., Masud, M.K. and Hossain, M. S. A., Pt-Modulated CuMnOx Nanosheets as Catalysts for Toluene Oxidation. ACS Applied Nano Materials, 2021, 4, 7, 6637–6647.
  • 6. Sharma, S., Masud, M.K., Kaneti, Y.V., Rewatkar, P., Koradia, A., Hossain, M.S.A., Yamauchi, Y., Popat, A. and Salomon, C., Extracellular Vesicle Nanoarchitectonics for Novel Drug Delivery Applications. Small, 2021, 2102220.
  • 7. Salahuddin, B., Masud, M.K., Aziz, S., Liu, C.H., Amiralian, N., Ashok, A., Hossain, S.A., Park, H., Wahab, M.A., Amin, M.A. and Chari, M.A., κ-Carrageenan Gel Modified Mesoporous Gold Chronocoulometric Sensor for Ultrasensitive Detection of microRNA. Bulletin of the Chemical Society of Japan, 2021.
  • 8. Ahmed, E., Masud, M.K., Hossain, M.S.A., Sina, A.A.I., Yamauchi, Y. and Trau, M., Nanostructured mesoporous gold electrodes detect protein phosphorylation in cancer with electrochemical signal amplification, Analyst, 2020, 145, 6639-6648. (‡equal contributor).
  • 9. Masud, M.K., Rabbee G.M., Aziz, N.B., Stevens, C.H., Do-Ha, D., Yang, S., Blair, I.P., Hossain, M.S.A., Shim, Y.-B., Ooi, L., Yamauchi, Y. and Shiddiky, M.J.A., Electrochemical Detection of Motor Neuron Disease (MND) Derived Exosomal miRNA at Attomolar Sensitivity, ChemElectroChem, 2020, 7, 3459 – 3467.
  • 10. Lim H, Kim J, Kani K, Masud M.K, Park H, Kim M, Alsheri S.M, Ahamad T, Alhokbany N, Na J, Malgras V., Bando Y. and Yamauchi, Y., Designed Patterning of Mesoporous Metal Films Based on Electrochemical Micelle Assembly Combined with Lithographical Techniques, Small, 2019, 1902934.
  • 11. Park, H.,¥ Masud, M.K.,¥ Na, J., Hossain, M.S.A. and Yamauchi, Y., Mesoporous Gold-Silver Alloy Films for Amplification-Free Ultra-Sensitive microRNA Detection, Journal of Materials Chemistry B, 2020, 8, 9512-9523.
  • 12. Pham, T.P., Qamar, A., Dinh, T., Masud, M.K., Rais-Zadeh, M., Senesky, D.G., Yamauchi, Y., Nguyen, N.T., and Phan, H.-P., Toward the next generation of nanoelectromechanical systems for environmental monitoring, Advanced Science, 2020, 7, 2001294
  • 13. Masud, M.K., Na, J., Lin, T.-E., Malgras, V., Preet, A., Sina, A.A.I., Wood, K., Billah, M., Kim, J., You, J., Kani, K., Whitten, A., Nguyen, N.-T., Shiddiky, M.J.A., Trau, M., Hossain, M.S.A. and Yamauchi, Y. Mesoporous Gold Biosensor for Electrochemical Detection of Attomolar MicroRNA, Biosensors and Bioelectronics, 2020, 112429
  • 14. Azhar, A., Li, Y., Cai, Z., Zakaria, M.B., Masud, M.K., Hossain, M.S.A., Kim, J., Zhang, W., Na, J., Yamauchi, Y. and Hu, M., Nanoarchitectonics: A New Materials Horizon for Prussian Blue and Its Analogues. Bulletin of the Chemical Society of Japan, 2019, 92, 875-904.
  • 15. Yadav, S., Kashaninejad, Masud, M.K., N., Nguyen, N.T., Shiddiky, M.J.A., Autoantibodies as Diagnostic and Prognostic Cancer Biomarker: Detection Techniques and Approaches, Biosensor and Bioelectronics, 2019, 139, 111315.
  • 16. Phan H.P, Zhong Y, Nguyen T.K, Park Y, Dinh T, Song E, Vadivelu R.K, Masud M.K, Li J., Shiddiky M.J.A., Dao D. Yusuke, Y., Rogers, J.A. and Nguyen, N.T., Long-Lived, Transferred Crystalline Silicon Carbide Nanomembranes for Implantable Flexible Electronics, ACS Nano, 2019, 13, 11572-11581.
  • 17. Boriachek, K., Masud, M.K., Palma, C., Phan, H.P., Yamauchi, Y., Hossain, M.S.A., Nguyen, N.T., Salomon, C. and Shiddiky, M.J.A., Avoiding Pre-Isolation Step in Exosome Analysis: Direct Isolation and Sensitive Detection of Exosomes Using Gold-Loaded Nanoporous Ferric Oxide Nanozymes. Analytical Chemistry, 2019, 89, 11005-11013.
  • 18. Phan, H.P.¥, Masud, M.K.¥, Vadivelu, R.K., Dinh, T., Nguyen, T.K., Ngo, K., Dao, D.V., Shiddiky, M.J.A., Hossain, M.S.A., Yamauchi, Y., and Nguyen, N.T., Transparent crystalline cubic SiC-on-glass electrodes enable simultaneous electrochemistry and optical microscopy, Chemical Communication, 2019, 55, 7978-7981 (¥equal contributor).
  • 19. Tanaka, S.,¥ Masud, M.K.,¥ Kaneti, Y.V., Shiddiky, M.J.A., Fatehmulla, A., Aldhafiri, A.M., Farooq, W.A., Bando, Y., Hossain, M.S.A. and Yamauchi, Y., Enhanced Peroxidase Mimetic Activity of Porous Iron Oxide Nanoflakes, ChemNanoMat, 2019, 5, 506-513.
  • 20. Masud, M.K., Billah, M.M., Kim, J., Wood, K., Shiddiky, M.J.A., Nguyen, N.T., Parsapur, R.K., Selvam, P., Hossain, M.S.A., and Yamauchi, Y., Nanoarchitectured peroxidase-mimetic nanozymes: mesoporous nanocrystalline α- or γ-iron oxide?, Journal of Material Chemistry B, 2019, 7, 5412-22.
  • 21. Masud, M.K., Umer, M., Hossain, M.S.A., Yamauchi, Y., Nguyen, N.T. and Shiddiky, M.J.A., Nanoarchitecture Frameworks for Electrochemical miRNA Detection, Trends in Biochemical Sciences, 2019, 44, 433-452.
  • 22. Masud, M.K, Younus M, Hossain, M.S.A, Bando Y, Shiddiky, M.J, and Yamauchi Y, Superparamagnetic Nanoarchitectures for Disease-Specific Biomarker Detection, Chemical Society Review, 2019, 48, 5717-5751.
  • 23. Islam, M.N., Gorgannezhad, L., Masud, M.K., Tanaka, S., Hossain, M.S.A., Yamauchi, Y., Nguyen, N.T. and Shiddiky, M.J.A., 2018. Graphene‐Oxide‐Loaded Superparamagnetic Iron Oxide Nanoparticles for Ultrasensitive Electrocatalytic Detection of MicroRNA, ChemElectroChem, 2018, 5, 2488-2495.
  • 24. Gorgannezhad, L., Umer, M., Masud, M.K, Hossain, M.S.A., Tanaka, S., Yamauchi, Y., Salomon, C., Kline, R., Nguyen, N.T. and Shiddiky, M.J.A., Detection of FGFR2: FAM76A Fusion Gene in Circulating Tumor RNA Based on Catalytic Signal Amplification of Graphene Oxide‐loaded Magnetic Nanoparticles, Electroanalysis, 2018, 30, 2293–2301.
  • 25. Bhattacharjee, R., Tanaka, S., Moriam, S., Masud, M.K., Lin, J., Alshehri, S.M., Ahamad, T., Salunkhe, R.R., Nguyen, N.T., Yamauchi, Y. and Hossain, M.S.A. Porous nanozymes: the peroxidase-mimetic activity of mesoporous iron oxide for the colorimetric and electrochemical detection of global DNA methylation, Journal of Material Chemistry B, 2018, 6, 4783-4791.
  • 26. Islam, M.N., Masud, M.K., Nguyen, N.T., Gopalan, V., Alamri, H.R., Alothman, Z.A., Al Hossain, M.S., Yamauchi, Y., Lam, A.K.Y. and Shiddiky, M.J.A., Gold-loaded nanoporous ferric oxide nanocubes for electrocatalytic detection of microRNA at attomolar level, Biosensors and Bioelectronics, 2018, 101, 275-281.
  • 27. Islam, M.N., Gopalan, V., Haque, M.H., Masud, M.K., Al Hossain, M.S., Yamauchi, Y., Nguyen, N.T., Lam, A.K.Y. and Shiddiky, M.J.A., A PCR-free electrochemical method for messenger RNA detection in cancer tissue samples, Biosensors and Bioelectronics, 2016, 98, 227-333.
  • 28. Haque, M.H., Gopalan, V., Islam, M.N., Masud, M.K., Bhattacharjee, R., Al Hossain, M.S., Nguyen, N.T., Lam, A.K. and Shiddiky, M.J.A., Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry, Analytica Chimica Acta, 2017, 976, 84-93.
  • 29. Islam, M.N., Masud, M.K., Haque, Hossain, M.S., Yamauchi, Y., Nguyen, N.T. and Shiddiky, M.J.A., RNA Biomarkers: Diagnostic and Prognostic Potentials and Recent Developments of Electrochemical Biosensors, Small Methods, 2017, 1, 1700131.
  • 30. Yadav, S., Masud, M.K., Islam, M.N., Gopalan, V., Lam, A.K., Tanaka, S., Nguyen, N.T., Hossain, M.S., Li, C., Yamauchi, Y. and Shiddiky, M.J.A., Gold-Loaded Nanoporous Iron Oxide Nanocubes: A Novel Dispersible Capture Agent for Tumor-Associated Autoantibodies Analysis in Serum, Nanoscale, 2017, 9, 8805-8814.
  • 31. Hossain, T., ¥ Mahmudunnabi, G.,¥ Masud, M.K.,¥ Islam, M.N., Ooi, L., Konstantinov, K., Al Hossain, M.S., Martinac, B., Alici, G., Nguyen, N.T. and Shiddiky, M.J.A., Electrochemical biosensing strategies for DNA methylation analysis, Biosensors and Bioelectronics, 2017, 94, 63-73. (¥equal contributor).
  • 32. Masud, M.K., Islam, M.N., Haque, M.H., Tanaka, S., Gopalan, V., ALICI, G., Nguyen, N.T., Lam, A.K.Y., Hossain, M.S., Yamauchi, Y. and Shiddiky, M.J.A., Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA, Chemical Communications, 2017, 53, 8231-8234.
  • 33. Masud, M.K., Yadav, S., Islam, M.N., Nguyen, N.T., Salomon, C., Kline, R., Alamri, H.R., Alothman, Z.A., Yamauchi, Y., Hossain, M.S.A. and Shiddiky, M.J.A., Gold-Loaded Nanoporous Ferric Oxide Nanocubes with Peroxidase-Mimicking Activity for Electrocatalytic and Colorimetric Detection of Autoantibody, Analytical Chemistry, 2017, 89, 11005-11013.
  • 34. Rahman, M.M., Younus, M., Naher, M., Masud, M.K., Nomoto, A., Ogawa, A., Rudnick, A. and Köhler, A., Synthesis, spectroscopic characterization, thermal and luminescent properties of new organosulfur-functionalized platinum (II) bis (alkenylarylalkynyl) complexes, Journal of Organometallic Chemistry, 2016, 818, 185-194.
  • 35. Huq, M.M., Rahman, M.R., Naher, M., Khan, M.M.R., Masud, M.K., Hossain, G.M.G., Zhu, N., Lo, Y.H., Younus, M. and Wong, W.Y., Synthesis, Characterization and Catalytic Activities of Palladium (II) Nitroaryl Complexes, Journal of Inorganic and Organometallic Polymers and Materials, 2016, 26, 1243-1252

External Affiliations

  • Honorary Fellow (Jan 2021 to Dec 2023), Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ), Brisbane, QLD 4072, Australia
  • Honorary Research Fellow (Dec 2020 to Dec 2022), National Institute for Material Sciences (NIMS), Namiki, Tsukuba City, Ibaraki, Japan
  • Visiting Scholar (Aug 2016 to present), Queensland Micro- and Nanotechnology Centre, Griffith University, Nathan Campus, QLD-4111, Australia

Awards & Recognition

  • UQ Research Training Scholarship (July 2018 to June 2020), awarded by the University of Queensland, Saint Lucia, QLD, Australia.
  • Post-graduate Research Awards (PGRA) (2018-2020), the Australian Institute of Nuclear Science and Engineering (AINSE), Lucas Heights, NSW 2234, Australia
  • International Post-graduation Tuition Award (IPTA) and Matching Scholarship (Aug 2016 to Jun 2018), awarded by University of Wollongong, Wollongong, NSW-2522, Australia.
  • Distinction Award in graduate degree (2011), awarded by Shahjalal University of Science & Technology, Sylhet-3114, Bangladesh
  • Dean's Award for Outstanding Higher Degree by Research Theses 2020

Conference

  • 1. Masud, M.K., Nanoarchitectured Device for Early Disease Detection, International Conference on Materials Science and Engineering (Material Ocenia 2021), Pullman Brisbane King George Square Brisbane City QLD 4000, Australia (Invited Lecture)
  • 2. Bilkiss M., Shiddiky M.J.A., Masud M.K., Sambasivam, P., Bar, I., Brownlie, J., Ford, R., Electrochemical biosensor for the detection of Botrytis spp. in temperate legume Crops. (ICPPPS 2020: International Conference on Plant Physiology and Plant Science (ICPPPS 2020), Zurich, Switzerland. (Oral presentation)
  • 3. Ford, R., Bilkiss, M., Masud, M.K., Sambasivan, P., Bar, I., Shiddiky, M. J. A., Specific and sensitive nanoparticle-based electrochemical detection of Botrytis cinerea, a damaging fungal plant pathogen, 8th International Conference on Nanoscience and Nanotechnology (ICONN 2020), Brisbane, Australia. (Oral presentation)
  • 4. Masud, M.K., Shiddiky, M.J.A., Hossain, M.S.A., Yamauchi, Y., Mesoporous nanoarchitecture point-of-care detection system for clinically relevant microRNA, International Conference in Recent Advances in Chemistry (ICRAC-2020), Jagannath University, Dhaka, Bangladesh (Invited Lecture)
  • 5. Masud, M.K., Boriachek, K., Hossain, M.S.A., Yamauchi, Y., and Shiddiky, M.J., Pre-enrichment free Exosome Analysis: Direct Isolation and Detection of Exosomes using Gold-Loaded Nanoporous Ferric Oxide Nanozymes, 21st Australia and Newzealand Electrochemistry Symposium 2019, Brisbane, Australia. (Poster presentation; Award: Analytical Methods Poster Prize)
  • 6. Masud, M.K., Billah, M.M., Kim, J., Hossain, M.S.A., and Yusuke, Y., Next-generation peroxidase-mimetic nanozymes: selection of mesoporous nanocrystalline α- or γ-iron oxide? AIBN Student Conference 2019, Brisbane (St Lucia), Australia, (Oral Presentation)
  • 7. Masud, M.K., Yamauchi, Y., Materials space-tectonics: A conceptual paradigm for disease-specific biomarker detection, Workshop on sustainable productive farming – what can nanotechnologies offer? Nathan Campus, Griffith University, QLD 4111, Australia (Invited Lecture)
  • 8. Masud, M.K., Yadav, Islam, M.N., Hossain, M.S.A., Yamauchi, Y., and Shiddiky, M.J.A., Nanoporous Peroxidase: Gold-Loaded Ferric Oxide Nanocubes for Electrochemical and Colorimetric Detection of Autoantibody, 9th International Nanomedicine Conference (oznanomed 2018), Sydney, Australia (Oral Presentation).
  • 9. Masud, M.K., Wood, K. Shiddiky, M.J.A., Kani, K., Kim, J., Hossain, M.S.A., and Yamauchi, Y., Electrochemical fabrication of mesoporous gold-electrode towards the ultrasensitive detection of microRNA, AINSE/ANBUG Neutron Scattering Symposium 2018, Sydney, Australia (Poster presentation; Award: First Prize for Outstanding Poster)

Teaching

  • Biophysical Chemistry I & II
  • Bioorganic Chemistry I & II
  • Enzymology I & II
  • Metabolism I & II
  • Organic reaction Mechanism
  • Chemistry of Natural Products
  • Magnetic Material Synthesis and Characterizations

Graduate Supervision

  • Hyeongyu Park (PhD; 2020-2022), Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ), Brisbane, QLD 4072, Australia.
  • S M Azad Hossain (PhD; 2020-2023), Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ), Brisbane, QLD 4072, Australia.
  • Javeria Bashir (PhD; 2021-2023), Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ), Brisbane, QLD 4072, Australia.
  • Xuan Lin (MS; 2021), Institute of Molecular Bioscience, The University of Queensland (UQ), Brisbane, QLD 4072, Australia.
  • Rashadul Islam (BSc Project; 2016), Department of Biochemistry and Molecular Biology, Shahjalal University of Sciene and Technology (SUST), Sylhet-3114, Bangladesh
  • Pushpita Sharker (BSc Project; 2015), Department of Biochemistry and Molecular Biology, Shahjalal University of Sciene and Technology (SUST), Sylhet-3114, Bangladesh