Faculty Profile

Dr. Md Jahangir Alam

Professor

Contact Information

  • Office Address: Department of Genetic Engineering & Biotechnology, Shahjalal University of Science and Technology, Sylhet-3114, Bangladesh
  • Phone: +8801911939040
  • Email: jahangir-btc@sust.edu, jalambioru@yahoo.com

Biography

Dr. Md. Jahangir Alam was born on 29th October of 1979, in a decent muslim family of village Jagadish, Itakumari under Rangpur district. He is the only son of Hafez Md Nurul Islam and Most. Latifa Begum and having two sisters. His elementary education was started on 1984 in Annadanagar Primary School, Pirgachha, Rangpur and then he completed his Secondary School Certificate (SSC) examination on 1994 from Annadanagar M. L. High School, Pirgachha, Rangpur. After his SSC education, he admitted to Carmichael College, the renowned college of North-Bengal and successfully passed the Higher Secondary Certificate (HSC) Examination on 1996. Afterword, he admitted to the Department of Biochemistry and Molecular Biology, University of Rajshahi as an undergraduate student and graduated from the same department on 2004. He received the government scholarship in his every stages of educational life. Just after his graduation, on 1st December, 2004; he joined as a lecturer of Biotechnology (at present Genetic Engineering and Biotechnology), Shahjalal University of Science and Technology, Sylhet, Bangladesh and started his career. On October 2010, he went to Tokyo University of Science to attend PhD program under the Japanese Government Scholarship (MEXT) and on 19th March, 2014, he awarded Doctor of Engineering (Super Grade) degree from the Department of Biological Science and Technology under the faculty of Industrial Science and Technology, Tokyo University of Science, Japan. By this time, he visited many countries like Japan, USA, Brazil, India, China, Sri Lanka, Malaysia, and Panama City. At present, he is serving as a professor in the department of Genetic Engineering and Biotechnology, Shahjalal University of Science and Technology, Bangladesh.

Education

  • Doctor of Engineering (D. Engg.) finished on 19th March, 2014; Super Grade; from the Department of Biological Science and Technology under the faculty of Industrial Science and Technology, Tokyo University of Science, JAPAN. Field of Specialization: PCR amplification, cloning, expression and purification of proteins. Protein-protein interaction, characterization and X-ray crystallography of protein.
  • Master of Science (M.Sc.) in 2000 (Exam. held in 2002), First Class; Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, BANGLADESH Major Courses: Biophysical Chemistry, Intermediary Metabolism, Endocrinology & Clinical Biochemistry, Molecular Biology & Genetic Engineering. Field of Specialization: Enzyme and Protein Chemistry
  • Bachelor of Science (B.Sc.) in 1999 (Exam. held in 2001), First Class; Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, BANGLADESH Major Courses: Biophysical Chemistry, Bioorganic Chemistry, Basic Biochemistry, Molecular Biology, Biomolecules, Human Physiology, Enzyme & Enzyme Kinetics, Protein Technology, Nutrition, Microbiology, Immunology, Intermediary Metabolism, Bioenergetics. Minor Courses: Mathematics, Botany
  • Higher Secondary Certificate in 1996, First Division; Carmichael College, Rangpur under Rajshahi Education Board, BANGLADESH
  • Secondary School Certificate in 1994, First Division; Annadanagar M. L. High School, Pirgachha, Rangpur under Rajshahi Education Board, BANGLADESH

Research Interests

  • Enzyme and protein technology- cloning, expression, and purification of protein, biochemical characterization (enzymatic assay, protein-protein interaction, protein-ligand/substrate interaction etc) of protein, protein crystallization, subunit assembly of protein. Biomedicine and medicinal plants- anti-microbial, anti-diabetic, anti-oxidant, cytotoxic activity of plant extracts; in vivo and in vitro characterization of plant-extracts.

Active Research Project

  • 1. "Inhibition of key digestive enzymes Linked to Type 2 Diabetes by the Extracts of Raw and BoiledAllium sativum (Garlic) to Control Diabetes Mellitus" funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2022-2023 (as Principal investigator).

Previous Research Project

  • 1. “Extraction and Characterization of Remedial Compounds from Selected Medicinal Plants to Evaluate Anti-Microbial Activities” funded by Ministry of Science and Technology, Bangladesh; 2015-16 (as Principal Investigator).
  • 2. “Isolation and Pharmacological Evaluation of Flavonoid Compounds from Tridax procumbens for Anti-Arthritis Potentials in Mice Model” funded by University Grants Commission Bangladesh, Dhaka, Bangladesh; 2015-2016 (as Co-investigator).
  • 3. “Scale-up the Production of Protease and Cellulase of Bacterial and Fungal Isolates Using Municipal Solid Wastes and Their Purification for Molecular Characterization” funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2014-2015 (as Co-investigator).
  • 4. "Bioconversion of Organic Municipal Solid Wastes into Bioresources through Production of Industrially Important Enzymes and Biodiesel" funded by Ministry of Education, Government of the People’s Republic of Bangladesh 2016-2017 (as Co-investigator).
  • 5. "In vivo and Biochemical Assessments of Nutritional and Medicinal Values of Satkara (Citrus macroptera) Fruits in Its Maturity Stages" by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2016-2017 (as Principal Investigator).
  • 6. "Biochemical and Molecular Characterization of Hilsa Shad, Tenualoseilisha for Natural Stock Management in Bangladesh" funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2017-2018 (as Co-investigator).
  • 7. "In vitro Inhibition of Key Enzymes Linked to Type 2 Diabetes by Protein Extracts from Piper betle Leaves: A Novel Approach to Manage Diabetes Mellitus" funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2018-2019 (as Principal Investigator).
  • 8. "Inhibition of Key Enzymes Linked to Type 2 Diabetes by Protein Extracts from Cucumber (Cucumis sativus) to Manage Diabetes Mellitus" funded by Ministry of Science and Technology, Bangladesh; 2018-2019 (as Principal Investigator).
  • 9. "Development of Low-cost On-device Cell Culturing System Using Superabsorbent Pad-based Passive Pump" funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2019-2020 (as Co-investigator).
  • 10. "Inhibition of Key Digestive Enzymes Linked to Type 2 Diabetes by the Extracts of Arachis hypogaea and Cinnamomum tamala to Manage Diabetes Mellitus" funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2020-2021 (as Principal Investigator).
  • 11. "Inhibition of α-amylase and α-glucosidase Linked to Type 2 Diabetes by the Extracts of Red Pitaya Fruit (Hylocereus polyrhizus) to Control Diabetes Mellitus" funded by University Research Centre, Shahjalal University of Science and Technology, Sylhet, Bangladesh; 2021-2022 (as Principal investigator)

External Affiliations

  • Life time member of Bangladesh Association of Biotechnology (BABT)

Journal Publications

  • 1. Inhibition of Key Digestive Enzymes Linked to Type 2 Diabetes Mellitus by Piper betle L. Leaf Extracts to Manage Diabetes in an Alternative Way
  • 2. Blood biochemical parameters for assessment of COVID-19 in diabetic and non-diabetic subjects: a cross-sectional study
  • 3. Evaluation of Invertase Inhibition Activities and Cytotoxicity of Ethanol and Acetone Extracts of Swietenia macrophyllia Leaves, Syzygium cumini and Trigonella foenum-graecum Seeds
  • 4. Evaluation of α-Amylase Inhibition and Cytotoxic Activities of the Arachis hypogaea and Cinnamomum tamala
  • 5. Relationship among obesity, blood lipids and insulin resistance in Bangladeshi adults
  • 6. Identification of AcrAB-TolC Efflux Pump Genes and Detection of Mutation in Efflux Repressor AcrR from Omeprazole Responsive Multidrug-Resistant Escherichia coli Isolates Causing Urinary Tract Infections
  • 7. Characterization of multi-drug resistant Klebsiella pneumoniae isolates from urinary tract infected-women in Sylhet city, Bangladesh
  • 8. Targeting of Virulence Factors and Plasmid Profiling of Klebsiella pneumoniae Causing Urinary Tract Infection in Sylhet City of Bangladesh
  • 9. Miah, M. F., Alam, M. J., Roy, N. G., and Deb, P. (2017) Kosh O Anobic Jibbijnan (Cell and Molecular Biology), Mullick Brothers, 42, Banglabazar, Dhaka-1100, ISBN: 984-8272-76-3, Page-312 (Bengali Book).
  • 10. Effect of Intensity of Cigarette Smoking on Leukocytes among Adult Men and Women Smokers in Bangladesh
  • 11. In Vitro Antioxidant Activity and Cytotoxicity of The Ethanolic Extracts of Satkara (Citrus Macroptera) Fruit Peels at Different Maturity Stages.
  • 12. Proximate Analysis and Assessment the Physical Characteristics of Different Types of Duck Eggs in Bangladesh
  • 13. Ahmad, I., Islam, M. S., Hossain, M. S., Alam, M. J., Islam, K. (2016) The effect of different groups of fangicides in controlling black rot (Corticium spp.) disease and yield of tea. Journal of Global Biosciences 5: 4062-4070.
  • 14. Al Mamun, M. A., Islam, K., Alam, M. J., Khatun, A., Alam, M. M., Alim Al?Bari, M.A., and Alam, M. J. (2015). Flavonoids isolated from Tridax procumbens (TPF) inhibit osteoclasts differentiation and bone resorption. Biol Res 48:51; DOI 10.1186/s40659-015
  • 15. Ashrafee,T. S., Alam, M. J., Barua, R., Khan, Z. K., Alam, M. J., and Al Mamun, M. A. (2015). Antibiotic-Herbal sensitivity and diversity of plasmids of Xanthomonas campestris in Sylhet region of Bangladesh. Asian J.Microbiol. Biotech.Environ. Sci.17(4): 851-857.
  • 16. Alam, M. J., Yamato, I., Arai, S., Saijo, S., Mizutani, K., Ishizuka-Katsura, Y., Ohsawa, N., Terada, T., Shirouzu, M., Yokoyama, S., Iwata, S., Kakinuma, Y., and Murata, T. (2013) Mutant LV476-7AA of A-subunit of Enterococcus hirae V1-ATPase: High affinity of A3B3 complex to DF axis and low ATPase activity
  • 17. Gulshan, R., Sarwar, M. T., Mamun, M. A., Alam, M. J., Hossain, S., Alam, M. M. (2013) Comparative study of antibacterial activity of vancomycin and chemically treated chitosan prepared from shrimp (Macrobrachium rosenbergii) waste. International Journal of Nutrition and Food Sciences 2(6): 307-311; doi: 10.11648/j.ijnfs.20130206.17.
  • 18. Alam, M. J., Arai, S., Saijo, S., Suzuki, K., Mizutani, K., Ishizuka-Katsura, Y., Ohsawa, N., Terada, T., Shirouzu, M., Yokoyama, S., Iwata, S., Kakinuma, Y., Yamato, I., and Murata, T. (2013) Loose binding of the DF axis with the A3B3 complex stimulates the initial activity of Enterococcus hirae V1-ATPase. PLoS ONE 8(9): e74291; doi: 10.1371/journal.pone.0074291.
  • 19. Miah, M. F., Alam, M. J., Rahman, M. M., Roy, N. G., and Deb, P. (2008) Gene Prokowshol O Jaiboprojukti (Genetic Enginnering and Biotechnology), Mullick Brothers, 42, Banglabazar, Dhaka-1100, ISBN: 984-8272-33-X, Page-308 (Bengali Book).
  • 20. Alam, M. J., Rahman, M. H., and Sayem, S. M. A. (2007) Extraction, partial purification and characterization of tomato invertase. Proc. Pakistan Acad. Sci. 44(2): 97-103.
  • 21. Miah, M. F., Sayem, S. M. A., Alam, M. J., Roy, N. G., and Deb, P. (2007) Anobic Jibbijnan O Anujib Bijnan (Molecular Biology & Microbiology), Mullick Brothers, 42, Banglabazar, Dhaka-1100, ISBN: 984-8272-30-5, Page-327 (Bengali Book).
  • 22. Alam, M. J., Rahman, M. H., Mamun, M. A., Ahmad, I., and Islam, K. (2006) Enzyme activities in relation to sugar accumulation in tomato. Proc. Pakistan Acad. Sci. 43(4): 241-248.
  • 23. Sayem, S. M. A., Alam, M. J., and Hoq, M. M. (2006) Effect of temperature, pH, and metal ions on the activity and stability of alkaline protease from novel Bacillus licheniformis MZK03. Proc. Pakistan Acad. Sci. 43(4): 257-262.

Teaching

  • Biochemistry
  • Molecular Biology
  • Enzymology
  • Metabolism
  • Bioenergetics
  • Techniques in Molecular Biology
  • Molecular Biology of Diseases
  • Protein and Enzyme Chemistry

Awards & Recognition

  • Dr. Jahangir was awarded Japanese Government Scholarship (MEXT Scholarship) for 3 years and 6 months for the doctoral course on 2010.
  • Shaheed Shamsuzzoha Hall, University of Rajshahi, Bangladesh, awarded a gold medal for academic excellence in B.Sc. (Honors) examination.

Graduate Supervision

  • 1. MS, PhD